Thursday, July 02, 2020

The latest attempt at an HIV vaccine has failed, as researchers announced Monday they have stopped giving the experimental shots in a major study. The study had enrolled more than 5,400 people since 2016 in South Africa, a country with one of the world’s highest HIV rates.

Last month, monitors checked how the study was going and found 129 HIV infections had occurred among the vaccine recipients compared with 123 among those given a dummy shot, according to the US National Institutes of Health.

“An HIV vaccine is essential to end the global pandemic and we hoped this vaccine candidate would work. Regrettably, it does not,” said NIH infectious diseases chief Dr Anthony Fauci.

There were no safety concerns, but NIH, which sponsored the study, agreed that vaccinations should stop.

The experimental shot was based on the only vaccine ever shown to offer even modest protection against HIV, one that was deemed 31% effective in Thailand.

That wasn’t good enough for real-world use but gave scientists a starting point.

They beefed up the shot and adapted it to the HIV subtype that’s common in southern Africa.

Two other large studies, in several countries, are under way testing a different approach to a possible HIV vaccine.

NEW YORK (AP) — After voicing support for Woody Allen and criticizing cancel culture, Spike Lee apologized Saturday for words he said were “wrong.” In an interview Friday on the New York radio station WOR 710, Lee called Allen “a great, great filmmaker.” “This cancel thing is not just Woody. And I think that when we look back on it, (we’re) gonna see that, short of killing somebody, I don’t if you can just erase somebody like they never existed. Woody’s a friend of mine,” said Lee. “I know he’s going through it right now.”

 

NEW YORK (AP) — Gary Phillips, a prize-winning crime novelist from Los Angeles, grew up on TV shows that showed a world nothing like the one he lived in. “I watched them all, ‘Dragnet,’ ‘Adam 12,’ ‘The Wild, Wild West,’ ‘Mannix,’ ‘Cannon,’ ‘Peter Gunn’ reruns and on and on. Now these were white guys and they were tough but fair and even-handed,” he told The Associated Press in a recent email, referring to popular programs mostly from the 1960s and 1970s. “I remember a ‘Dragnet’ episode where tight-ass Joe Friday solved racism among black and white officers in a weekend retreat. But I was a kid growing up in South Central and even then some part of me knew a lot of this was jive. We knew the cops out of Newton and 77th Division policed the ’hood a lot different than shown on TV.”

NEW YORK (AP) — An angry and emotional Dave Chappelle spoke on the killing of George Floyd in a surprise Netflix special, saying America was being punished for its mistreatment of black men. “I don’t mean to get heavy but we got to say something,” said Chappelle, who added that America is enduring “the wrath of God” for a string of police assaults on black men. The special was released Thursday and is streaming free on Netflix’s comedy YouTube channel. It was taken from a show at an outdoor pavilion in Yellow Springs, Ohio, with about 100 attendees on June 6.

Nanci Ryder, a powerful Hollywood publicist and co-founder of BWR Public Relations who became close to such stars as Renée Zellweger and Courteney Cox, died Thursday of Lou Gehrig’s disease in Los Angeles. She was 67. Ryder was diagnosed with amyotrophic lateral sclerosis — or ALS — in 2014. The neurodegenerative disease gradually claimed her ability to walk, talk, eat and move. Her death was announced by publicist Lynda Dorf. Ryder’s clients — including Michael J. Fox, Reese Witherspoon, Viggo Mortensen and Sarah Michelle Gellar — blossomed into close friends. Zellweger thanked Ryder in her best actress acceptance speech when she won the Academy Award for “Judy” earlier this year. Witherspoon called her a “second mother.”